The Croyle Lab

The laboratories of Maria A. Croyle RPh., PhD.
The University of Texas at Austin's College of Pharmacy

Dr Maria A. Croyle RPh., PhD is a Professor of Pharmaceutics at The University of Texas at Austin College of Pharmacy where she has lead a busy research lab in pursuit of a single-dose, long-lasting Adenovirus-based Ebola vaccine, as well as studies in drug metabolism, novel vaccine formulations and other viral vectors.
Her students have come from all over the world to be challenged by the plethora of skill sets represented in such an innovative research environment.


Jul
16
to Jul 18

Irnela Presents Research at Annual Meeting of The Controlled Release Society in Boston, MA

Dr Croyle and Irnela traveled to Boston, MA to attend the annual meeting of The Controlled Release Society.  Irnela won a Graduate Student Travel Award and presented a poster detailing her latest research titled "Stability and Release Profiles of Adenovirus in Thin Films Used in the Development of an Oral Ebola Vaccine".

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Jun
13
1:30 PM13:30

Croyle Lab Film Technology Awarded first U.S. Patent

Research that began in 2009 finally completed its long trek through patent approval.  Titled, "Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine", this patent provides a stable legal foundation as we find ourselves approached by more potential investors from the pharmaceutical industry.
U.S. Patent: 9,675,550

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Apr
22
to Apr 26

Kristina Presents Research at Experimental Biology 2017

Kristina was recognized by the American Society of Pharmacology and Experimental Therapeutics for her novel research identifying the role TALEN adapter proteins play in the regulation of hepatic drug metabolism.  She received a graduate student travel award from ASPET to present a poster and oral presentation at the Experimental Biology 2017 conference in Chicago, IL.

Kristina's Abstract: "Tipping the Balance of Hepatic CYP3A4 Activity Through Integrin-Mediated Outside-In and Inside-Out Signaling

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Apr
14
1:30 PM13:30

Croyle Lab Members Present Research Posters at Annual CoP Research Day

Each year the University of Texas College of Pharmacy holds a Research Day event to allow students to share their projects with their peers.  This year, the Croyle Lab took this opportunity to present four different aspects of our research in the form of posters.

Christine - "Cinnamon and Spice as Excipients Are Nice: Impact of Flavoring Agents on the Physical Properties of Dissolvable Films"
Irnela - "Stability and Release Profiles of Adenovirus in Thin Films Used in the Development of an Oral Ebola Vaccine"
Kristina - "Are You Up to Date on Your Vaccines?  What You Need to Know About How Common Viruses and Their Vaccines Impact Your Drug Metabolism"
Jocelyne - "An Evaluation of Loading Efficiency of Protein in Thin Dissolvable Films"

Research Day 2017 Website Link

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Apr
12
1:30 AM01:30

Croyle Awarded $75k Janssen Award from J&J Next Gen Supply Chain Quickfire Challenge

Dr Croyle received a grant of $75,000 from the Johnson and Johnson Next Gen Supply Chain Quickfire Challenge and was recognized in front of industry peers for bringing forward a potential solution to key manufacturing and supply chain challenges that addresses the issues of cost and reliability in healthcare supply chains.

Dr Croyle’s winning solution is a physical film that has been shown to protect vaccines at room temperature and may have the same effect on monoclonal antibodies, which could be of great benefit in pharmaceutical Supply Chain. This innovation potentially could eliminate the need for refrigeration of some APIs (active pharmaceutical ingredients) and finished products—allowing for easier, less costly storage and transportation, as well as easier delivery to patients in remote areas across the globe and emerging markets.

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Feb
21
12:30 AM00:30

Croyle Lab Film Technology Selected for 2016-2017 Texas Health Catalyst Award

Dr Croyle delivered one of the winning pitches describing the lab's novel film technology.  The presentation titled "Dissolvable Film for Storage, Transport and Delivery of Thermolabile Therapeutics" was selected by a panel of venture capitalists and industry experts for additional funding to help bring the technology to market.

Texas Health Catalyst Award Announcement

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Updated:  August 10, 2023 by SCS